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Does Eliquis Make You Tired?

When prescribed with Eliquis, the majority of people would think that Eliquis will have side effects the same as any blood thinner or anticoagulant. Well, it's possible. Tiredness or fatigue is a reported side effect of taking a blood thinner. Now, the question arises, Does Eliquis make you tired?

What is Eliquis used for?

Eliquis is a brand-name prescription medication, an anticoagulant (blood thinner), which is FDA-approved to prevent or treat life-threatening blood clots that obstruct blood vessels in the body. Its active ingredient is Apixaban.

Specifically, Eliquis is indicated for use by adults to:

  • Prevent blood clot formation and risk of heart stroke in patients having nonvalvular atrial fibrillation (AFib).
  • Treat Deep Vein Thrombosis (DVT).
  • Treat Pulmonary Embolism (PE).
  • Avoid recurrence of a DVT or PE.
  • Prevent DVT that further could result in PE in patients who have undergone hip or knee replacement surgery.

After getting to know about Eliquis and its uses, the next thing that most people would want to learn about any medication is its side effects. One such doubtful side effect of Eliquis is tiredness or fatigue. You can learn more about this in the article “Does Eliquis make you tired”.

What are the most common side effects of Eliquis?

Minor side effects include:

  • Easy bruising
  • Nausea or Fainting
  • Slight bleeding that takes longer than usual to stop.
  • Anaemia (low count of red blood cells).
  • Skin rashes
  • Itching
  • Flushing

The potential serious side effects include:

  • Swelling under the skin.
  • Swollen tongue, throat, or mouth.
  • Unusual bleeding through mouth, nose, rectum, or vagina.
  • Bloody or black stools.
  • Dizziness
  • Weakness
  • Headache
  • Heavy menses

This is not an exhaustive list of side effects. To know whether tiredness is a side effect of Eliquis, go to the next section which describes Does Eliquis make you tired in detail.

Does Eliquis make you tired?


As per clinical studies done on , tiredness or fatigue is not a reported side effect. However, Eliquis can make its user tired, if the user’s blood count has drooped and he/she has developed anemia. Low blood cell count can lead to weakness, fatigue, dizziness, and shortness of breath. Those who are on blood thinner experience low blood cell count and nausea as its side effects besides bleeding-related issues. Therefore, as Eliquis is an anticoagulant (a blood thinner), it can make one feel tired.

Eliquis can affect blood pressure, which can sometimes lead to feelings of tiredness or lethargy. It can also change sleep patterns or quality which could lead to feelings of tiredness during the day It can also increase the risk of bleeding, and dehydration, which can also lead to fatigue.

In certain cases, the dosage of Eliquis may need adjustment. A dosage that is too high or too low for a particular person could potentially lead to fatigue. If one is taking Eliquis with other medications, there are chance that drug interactions can lead to fatigue as a side effect. If you or your known taking Eliquis feels tired on intake of Eliquis, informing a healthcare provider is a must and urgent. A healthcare provider can check through blood tests if the patient taking Eliquis has anemia and treat it.

What should I avoid while taking Eliquis to cope with Fatigue from Eliquis?


  • While on the course of Eliquis, doctors recommend watching for activities or sports that could increase the chances of an injury or bleeding.
  • Avoid brushing teeth, shaving unwanted hair, and using any sharp tools until all the side effects of taking Eliquis are known.
  • If Eliquis makes you fatigued, you need to get your blood tested for anemia and get it treated, take proper rest, eat healthily, and avoid any activities that would increase your tiredness or cause you harm while you are fatigued.
  • Avoid taking alcohol while taking his medicine as it can interact with Eliquis and increase your risk of bleeding. Also, take seven to eight hours of quality sleep each night, to avoid being sleep deprived.
  • Stress can exacerbate fatigue, so focus on stress-reduction techniques and perform meditation, deep breathing exercises, yoga, and light exercises like walking or gentle stretching that can improve your energy levels.
  • Eat a healthy diet to combat fatigue. Eat fruits, vegetables, lean proteins, and whole grains to ensure your body gets enough nutrition.

Eliquis Alternatives:

Does Eliquis make you tired? Then there are many direct oral anticoagulants available that can treat the same conditions as done by Eliquis. The alternative drugs may include Acova, Lovenox, Fragmin, Iprivask, Arixtra, and Angiomax.

Some foods, herbs, and dietary supplements are known to have blood thinning effects and so can be used in place of Eliquis. However, there are no double-blind, controlled clinical trials done to compare natural alternatives with other drug alternatives of Eliquis.

If Eliquis makes you tired? Some natural alternatives to Eliquis include:

  • Ginger: It has salicylate, the same active ingredient in aspirin, which works in stopping blood clot formation.
  • Garlic: It has antimicrobial as well as antiplatelet, blood thinning effects because of its components.
  • Turmeric: It has curcumin as its active ingredient. Curcumin may have anti-inflammatory and blood-thinning effects.

If you are interested in finding an alternative medication to Eliquis, you can talk about it with your healthcare provider. A healthcare provider can help you find another drug that works effectively for you without causing many side effects and even suggest natural alternatives to Eliquis.

FAQs:

Is Eliquis a blood thinner?

Eliquis is an anticoagulant that does not allow blood to form clots. Sometimes anticoagulants are referred to as a blood thinning class of medications although they do not work to make blood thinner. Blood thinners are medications that allow blood to flow smoothly through the veins and arteries, thereby preventing fatal blood clot formation and reducing the risk of strokes and heart attacks. Eliquis makes blood less able to form clots and is a powerful blood thinner.

Does Eliquis cause stomach problems?

Yes, as per clinical studies done on the Eliquis drug, both mild and serious stomach problems were reported. The potential stomach issues that showed up as side effects include nausea and gastrointestinal tract or stomach bleeding which can cause blood in stool, blood in vomit, and blood while coughing. There are also other potential side effects of taking Eliquis. The most common worry among people taking Eliquis is: Does Eliquis make you tired? The answer is it is not the common side effect and some people may experience fatigue as a side effect, while others may not.

Does Eliquis cause depression or anxiety?

As per clinical studies, there is no link between Eliquis and developing depression. Moreover, other studies on Eliquis have not viewed whether Eliquis causes anxiety.

What Foods to Avoid while on Eliquis?

There is no specific list of foods reported to cause negative interactions with Eliquis. However, there are certain foods, herbs, and spices that may increase or decrease Eliquis concentration in the body, thereby making Eliquis stronger or weaker anticoagulant. Certain foods that may increase Eliquis concentration in the body include lime juice, grapefruit juice, oats, wild blueberries, mangoes, and fish oil. Herbs, spices, and supplements that may increase or decrease Eliquis concentration in the body include chamomile, ginseng, St. John’s wort, garlic, ginger, rosemary, and cinnamon. Cardiovascular patients taking Eliquis should avoid the consumption of fat-rich food items and caffeinated drinks.

Can Eliquis cause hair loss?

Hair loss can be a potential concern for the unwanted effect of taking Eliquis. Although hair loss is not a reported common side effect, some clinical studies suggest a potential connection between Eliquis and hair loss in some users. But no exact mechanisms are known to date to tell how Eliquis could contribute to hair loss. Researchers propose several theories for this. Not everyone taking Eliquis experiences hair loss and if they do, its occurrence varies among people. Eliquis can have certain side effects, many people think that does Eliquis make you tired or causes anxiety or fever, this article has answered everything in detail.

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