ZETIA

Zetia is a brand/ trade name for the Ezetimibe drug. It contains the active ingredient Ezetimibe. Ezetimibe is a white crystalline solid, soluble in acetone, ethanol, and methanol and practically insoluble in water. Its chemical name is 1-(4- fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone. Ezetimibe is used to lower cholesterol levels by blocking the absorption of cholesterol in the small intestine.

In 2002, Zetia was FDA-cleared as a prescription drug to treat hyperlipidemia (high cholesterol) in adults and children aged 10 years and above. This drug helps reduce levels of total and bad (LDL) cholesterol in the blood in individuals who cannot control their cholesterol levels solely with diet modifications and regular exercise. It works best when the patients follow medication, diet, and exercise routines.

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Zetia belongs to the drug class: 2 Azetidinones, Lipid Lowering Agents. It is a cholesterol absorption inhibitor. This drug class works to selectively inhibit the absorption of cholesterol and related phytosterols by the small intestine.

This drug specifically targets the mechanisms that are involved in cholesterol absorption, hence aiding in the reduction of cholesterol levels in the body. It is often used in combination with other lipid-lowering medications or as an adjunct to dietary and lifestyle modifications to manage elevated cholesterol levels.

Zetia medication is sold as tablets of 10mg strength. Learn more on Zetia Price with the top one pharmacy, CanadaPharmacyPro.

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Zetia is FDA-cleared to treat certain forms of high cholesterol.These include genetic conditions like:

• Primary hyperlipidemia
• Mixed hyperlipidemia
• Homozygous familial hypercholesterolemia
• Homozygous sitosterolemia

These conditions are the result of mutations in genes that control how cholesterol, triglycerides, and/or plant sterols are eliminated from the body.

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• A typical dose of Zetia is one 10mg tablet, once a day at the same time daily, with or without food.
• The patients must take Zetia exactly as prescribed by their doctor and as per the directions given on the prescription label.
• Specifically, it must be taken along with a low-cholesterol diet and may be consumed with other lipid-lowering drugs.

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Zetia drug comes in the form of easy-to-swallow tablets that are taken orally. It is available in convenient and simple-to-swallow tablet form. This oral route of administration ensures that the medication is taken orally, allowing for efficient bloodstream absorption.

With its tablet form, Zetia provides patients with an easy and accessible way to incorporate it into their daily healthcare regimen. By orally ingesting the medication, patients are able to adhere to their prescribed dosage and potentially experience improvements in their cholesterol levels, contributing to their overall health and well-being.

• Zetia can lead to mild or severe side effects.
• Its common side effects may include signs of having a cold like sneezing, stuffy nose, sore throat; diarrhea, joint pain, aching leg or arm, or muscle pain (when statin is taken along with Zetia).
• For some users, Zetia can result in allergic reactions and/or breakdown of muscle tissues that can lead to kidney failure.
• It’s advised to call a doctor immediately for medical help if experiencing unexplained muscle pain, weakness, or tenderness, usual tiredness, having dark urine, serious heart problems, serious eye problems, or any other side effects not mentioned here.

It’s important to discuss with the doctor the current intake of medications and supplements before taking Zetia. That’s because Zetia may cause drug-drug interactions with medications like:

• Blood thinners
• Anti-androgen medicines such as darolutamide
• HIV medications such as fostemsavir
• Anti-cancer medicines such as entrectinib
• Cholesterol medicines like colesevelam, cholestyramine
• Gemfibrozil
• Fenofibric acid
• Colestipol
• Cyclosporine; and many more prescribed or over-the-counter medicines and supplements.

• Zetia with statins is not indicated for people aged above 65 years or those having liver problems as it can cause severe muscle pain and damage and even result in severe kidney problems or liver damage.
• Drug intake is also not recommended for pregnant and breastfeeding women.
• Patients who have known hypersensitivity to any ingredient of Zetia tablets are also not indicated to take Zetia.

• If deciding to use Zetia, one must talk to one’s doctor to know about risks, drug interactions, and contraindications for the medicine and tell the doctor about allergies (if any).
• Zetia uses a specific statin or fenofibrate or any other medicine should be as per the directions provided on the product label and discussion with a doctor.
• If one has started taking Zetia, the doctor needs to keep checking whether the medicine is working or not. One must check with a doctor immediately, if experiencing any serious side effects or if one may be pregnant.
• While taking Zetia it is important to have a low-cholesterol diet. This means, avoiding fat-loaded foods and drinks that contain more bad cholesterol.
• In addition, the users may need to watch out for foods like grapefruit that can interact with Zetia, if taken with statin.

• Store Zetia Drug in a tightly closed container at room temperature.
• Heat, moisture, freezing conditions, and direct light, can spoil the medicine or cause it to lose its efficacy.
• The medicine must be kept away from the reach of the children.

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