SYMMETREL (AMANTADINE)

Symmetrel is used to treat Parkinson’s disease and symptoms resembling “Parkinson’s” such as stiffness or tremor, shaking, and repetitive uncontrolled muscle movements that may be caused by the use of certain drugs. The medicine is known by the generic name of Amantadine, an antiviral medicine that prevents the action of viruses in the body. The drug helps restore the balance of natural chemicals (neurotransmitters) in the brain which helps in the treatment of these conditions. The medicine contains hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate, as inactive ingredients.

Symmetrel is also employed in the management of certain types of flu (Influenza A). It is crucial to note that this medicine should not be considered in place of a yearly flu shot as the Centers for Disease Control recommends an annual flu shot to overcome new strains of the influenza virus.

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Symmetrel is categorized within a class of medications known as antiparkinsonian agents. It is used to alleviate the symptoms that are associated with Parkinson’s disease and related conditions. It restores the balance of natural chemicals (neurotransmitters) in the brain which helps to manage issues like stiffness, tremors, and involuntary muscle movements. It helps in managing symptoms of idiopathic parkinsonism and secondary parkinsonism.

It is also classified as an antiviral agent as it is used against the Influenza A virus, as it inhibits replication of the influenza A virus.

The medicine also acts as an NMDA receptor antagonist. This helps to contribute to its effects on Parkinson's disease.

Symmetrel is available in the following strengths:

• 50 mg
• 100 mg

These are the common dosages that are mostly available.

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The medicine is used to prevent and treat a specific type of flu (Influenza A). It does not work for the common cold and any other types of flu, or viral infections.

The drug is also used to treat Parkinson's or symptoms resembling this condition. It also helps in managing movement disorders by restoring the balance of natural chemicals (neurotransmitters) in the brain and helps manage issues like stiffness, tremors, and involuntary muscle movements.

Medicine also help manage extrapyramidal symptoms (EPS). It helps to manage symptoms like stiffness of the muscles, tremors, and other movement-related issues.

For the treatment of Influenza A: Take the medicine within 24 to 48 hours after flu symptoms begin. Symmetrel can be taken with or without food. It might be advisable to take this medicine before bedtime as directed by a doctor. Follow the doctor’s instructions diligently to ensure optimal effectiveness.

For the treatment of Parkinson's symptoms: The starting dose is 100 mg, but it can vary and should be determined by healthcare professionals. Do not stop using Symmetrel medicine suddenly as it can cause unpleasant withdrawal symptoms.

In the case of Symmetrel tablets, the route of administration is oral. It is to be taken by mouth. It is usually recommended to be swallowed with water, and the specific dosages and timing instructions are provided by prescribing healthcare professionals. It can be taken with or without food usually once or twice daily. Do not take more than prescribed by the doctor. This route of administration allows the drug to be absorbed through the digestive system into the bloodstream, where it can show its full effects. Consult the doctor, if you have any problems or face challenges while swallowing the tablet.

One must swallow the medicine as a whole and not crush, chew, or break it.

Common Symmetrel side effect includes:

• Bladder pain
• Joint swelling
• Constipation
• Seizures
• Depression
• Dry mouth
• Fainting
• Nausea
• Anxiety

Severe side effects:

• Purplish-red blotchy spots on the skin
• Swelling of the ankles/feet
• Difficulty urinating
• Vision changes
• Shortness of breath
• Muscle stiffness
• Fast heartbeat
• Unexplained fever
• Unusual strong urges (Increased gambling, and sexual urges)

Some of the drugs, products, and pills that are known to interact with Symmetrel include:

• Glaucoma medication
• Medicine that contains Sodium Bicarbonate
• Atropine
• Dicyclomine
• Glycopyrrolate
• Hyoscyamine
• Methscopolamine
• Propantheline
• Scopolamine
• Quinine
• Diuretics
• Phenothiazines

Before initiating Symmetrel or while on Symmetrel medication, there are a few precautions that need to be considered which include:

• If there have been any heart problems such as (a heart attack or life-threatening irregular heartbeat in the past six months) it is advised to consult the doctor before initiating the medicine.
• Diseases such as kidney failure or who are undergoing dialysis, liver disease, high or low blood pressure, dehydration, penis conditions such as angulation, fibrosis. In this condition medical consultation is required prior to initiating the use of Stendra medicine.
• It is advised to consult the doctor in case of leukaemia, multiple myeloma, eye problems, bleeding disorders, and active stomach ulcers.
• In the case of heart disease, diabetes, high cholesterol, high blood pressure, and certain eye problems there is a slightly greater chance of developing NAION if one takes Stendra.

• High protein meals or supplements should be avoided around the time of medication intake, as they tend to impact Symmetrel’s absorption.
• Do not smoke alcohol while taking this medicine.
• Avoid intake of junk food and soft drinks while using this medicine.
• Do not drink alcohol as it increases certain side effects.
• The dose of the medicine should be reduced in patients suffering from renal impairment or who are 65 years of age or older.
• Medicine should be carefully administered in patients with congestive heart failure, peripheral edema, or orthostatic hypotension.
• If you are pregnant, take medicine only after consulting a doctor.
• The medicine can cause dizziness or light-headedness. One must avoid activities that require alertness, like driving or operating machinery.

To ensure proper storage of Symmetrel tablets, follow these guidelines:

• Keep it at a controlled room temperature between 20-25 degrees Celsius.
It is recommended to keep it tightly closed in its original container. Keep it away from excessive heat, direct sunlight, and moisture. Keep it out of reach of children and pets.

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