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Rexulti is an atypical antipsychotic medication usually prescribed for the treatment of major depressive disorder in adults, Schizophrenia in adults and teenagers, and agitation associated with Dementia in Alzheimer's patients. Buy Rexulti online and manage psychosis without straining your budget!
Rexulti is a brand name for the active medication Brexpiprazole. It is a prescription drug that got FDA approval in 2015 for the treatment of Schizophrenia. In May 2023, Rexulti got another FDA clearance as the first supplemental drug for the treatment of agitation associated with dementia because of Alzheimer’s disease.
Rexulti contains Brexpiprazole as its active ingredient. Brexpiprazole belongs to a class of medications called atypical antipsychotics. It works by modulating the activity of certain neurotransmitters in the brain, including dopamine and serotonin. In schizophrenia, brexpiprazole helps to alleviate symptoms such as hallucinations, delusions, disorganized thinking, and social withdrawal. It acts as an antagonist at dopamine D2 receptors and serotonin 5-HT1A receptors, which helps to restore the balance of these neurotransmitters and improve overall mental functioning.
The following inactive ingredients are present in the medicine: corn starch, lactose monohydrate, low-substituted hydroxypropyl cellulose, hydroxypropyl cellulose, microcrystalline cellulose, hypromellose, magnesium stearate, talc., and colorants including iron oxide, titanium dioxide, and ferrosoferric oxide. Brexpiprazole is chemically designated as 7-{4-[4-(1-Benzothiophen-4-yl) piperazin-1-yl] butoxy} quinolin-2(1H)-one.
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Rexulti belongs to the pharmacological class Atypical antipsychotics, a Serotonin/Dopamine Activity Modulator (SDAM).
Serotonin-dopamine activity modulators are a class of drugs that can improve symptoms of psychiatric disorders like major depressive disorder, schizophrenia, and bipolar disorder by modulating the activity of two neurotransmitters in the brain: serotonin and dopamine. Both of these neurotransmitters help regulate mood and emotions. Dopamine is a happy hormone, responsible for pleasure sensation in addition to its role in movement, cognition, and emotions. Serotonin plays a role in the regulation of mood, behavior, cognition, sleep, and digestion.
SDAM modulates the activity of serotonin and dopamine by blocking the brain’s excitatory receptors and enhancing the activity of inhibitory receptors. Atypical antipsychotics have a lower affinity for dopamine receptors and greater serotonin receptors than typical antipsychotics.
Rexulti tablets come in 6 strengths:
The specific strength prescribed will depend on various factors, including the severity of the condition being treated, individual patient response, and the healthcare provider's clinical judgment.
Rexulti drug is given by doctors for the treatment of the following medical conditions:
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Dosing information for Adults with Major Depressive Disorder:
Dosing information for Adult Schizophrenic patients:
Dosing information for Paediatric Schizophrenic patients:
Dosing Information for Agitation Associated with Dementia Due to Alzheimer’s Disease in Adults:
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The common side effects of Rexulti include:
The rarely occurring serious side effects are:
So far there are 568 other drugs known to interact with Rexulti. Therefore, the patient must tell the doctor about the current intake of medications/supplements/substances before starting to take Rexulti alongside.
Rexulti is not safe for use by:
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Rexulti is costly because it is a new brand of medication whose generic version is not yet available. Genetic medication tends to be cheaper than brand medication. As Rexulti is a brand medication, a lot of research is put behind it to ensure its safety and effectiveness which adds to the total Rexulti cost.
Yes. Weight gain is one of the reported side effects of taking Rexulti in patients being treated for either Major Depressive Disorder or Schizophrenia. The possible reason behind weight gain could be loss of appetite and limited physical activity.
As per clinical studies done with Rexulti, for some patients results were noticeable within 1 or 2 weeks of starting the treatment. Schizophrenia and Depression patients could see final results in 6 weeks while it took 12 weeks for results to be noticed in Alzheimer’s patients having agitation associated with dementia.
Yes. Rexulti is an atypical antipsychotic- a drug class designed for the treatment of psychiatric conditions like Schizophrenia and Depression.
No. Rexulti is just a prescription medication for the treatment of psychotic symptoms in patients suffering from Schizophrenia, Major Depressive Disorder, and Alzheimer’s Disease.
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