PRILOSEC (OMEPRAZOLE)

Prilosec is a brand name for a generic medication called Omeprazole. It is available both over-the-counter and with a doctor’s prescription in the pharmacy stores for treating some conditions caused by stomach acid. It is FDA-approved for reducing acid production in the stomach, thereby treating conditions like gastroesophageal reflux disease (GERD), ulcers, and even Zollinger-Ellison Syndrome.

Prilosec delayed-release tablets/capsules contain Omeprazole Magnesium as the active ingredient and following inactive ingredients hypromellose, cellulose, lactose, disodium hydroxypropyl cellulose, hydrogen phosphate, sodium lauryl sulfate, mannitol, and other ingredients that make up the capsule shell. Omeprazole is a white to off-white crystalline powder, a substituted benzimidazole, with the chemical name 5-methoxy-2- [[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl]-1H-benzimidazole. If you want to purchase Prilosec at the best possible Prilosec cost, Buy Prilosec Online with CanadaPharmacyPro.

Prilosec belongs to the pharmacological class: Proton Pump Inhibitors. Proton pump inhibitors are the class of drugs that help treat acid reflux and other issues caused by stomach acid excess, at its root. This medicine works by blocking the H+/K+ ATPase enzyme irreversibly. This enzyme is the proton pump present in the parietal cells of the stomach wall and is responsible for regulating stomach acid production. Prilosec helps block enzyme activity and so is effective in reducing stomach acid production and providing heartburn relief. Its effect lasts all day and night, meaning round the clock.

Prilosec tablets/capsules have three strengths: 10mg, 20mg, and 40mg. The capsule shells are composed of the following ingredients gelatin-NF, FD&C Blue #1, FD&C Blue #2, D&C Red #7 Calcium Lake, FD&C Red #40, D&C Red #28, butyl alcohol, titanium dioxide, isopropanol, synthetic black iron oxide, and even D&C Yellow #10 (only in 10 and 40 strengths).

Prilosec is meant to reduce stomach acid production. It helps treat the following conditions caused by excess stomach acid production:

• Symptomatic Gastroesophageal reflux disease (GERD): It is a type of acid reflux that can affect one with a frequency of 2 times a week. It is a condition wherein stomach acid comes into the food pipe (esophagus) and causes discomfort. Heartburn is the major sign of GERD in which there is a burning sensation behind the breastbone in the middle of the chest. Prilosec OTC helps block heartburn and other symptoms of GERD. Its full effect takes anywhere from 1-4 days and provides 24-hour relief from heartburn.
• Erosive esophagitis: It is esophagus damage due to gastric acid-mediated GERD. Prilosec is given as a short-term treatment of erosive esophagitis or to promote the healing of esophagus damage.
• Active Benign Gastric Ulcer or Duodenal Ulcer: Prilosec can be a short treatment for the soreness of the lining of the esophagus, stomach, or small intestine resulting from more untreated acid reflux that leads to infection with Helicobacter pylori.
• Pathological Hypersecretory Conditions: Prilosec can be taken as a long-term treatment medication for other stomach acid-related conditions like Zollinger-Ellison Syndrome, Systemic Mastocytosis, and Multiple Endocrine Adenomas.

• The suggested dosage for treatment of active duodenal ulcer in adults is 20 mg pill taken once daily for 4 weeks.
• The suggested dosage for treatment of benign gastric ulcer in adults is a 40 mg pill taken once daily for 4-8 weeks.
• The suggested dosage for treatment of symptomatic GERD or heartburn relief is a 20 mg pill once daily for up to 4 weeks.
• The suggested dosage for the treatment of erosive esophagitis is 20 mg once daily for 4-8 weeks and the same for maintenance of healing but for a duration not longer than 1 year.
• The suggested dosage for the treatment of pathological hypersecretory conditions initially is 60 mg once daily and the maximum it’s up to 120 mg three times daily for a few years, as the doctor prescribes.

This medicine is available in tablets/capsules meant for oral administration. This allows one to make medicine easily with water. Also, the oral route ensures the easy absorption of the medicine through the digestive tract and further circulates in the body.

Some of the commonly reported side effects of taking Prilosec:

• Stomach ache
• Gas
• Diarrhea or Constipation
• Nausea
• Vomiting
• Headache
• Fever (especially in pediatric patients)
• Cold symptoms like sneezing, stuffy nose, and sore throat.

Some of the serious side effects of Prilosec:

• Severe stomach issues
• Kidney problems
• Convulsions or seizures
• New or unusual pain in hips, thighs, wrist, or back.
• Signs of allergic reaction such as hives; swollen face, throat, lips, or tongue; and troubled breathing.
• Signs of low magnesium include muscle spasms/ cramps, choking or coughing, dizziness, and irregular heartbeats.
• New or serious signs of lupus include skin rash on cheeks or arms which worsens with sunlight exposure and aching joint.

Here is a non-exhaustive list of drugs known to interact with Prilosec:

• Diazepam, Phenytoin, and Warfarin- Their concentrations in the blood rise when these drugs are taken with Prilosec.
• Ketoconazole- Its absorption and concentration in the blood are reduced when taken along with Prilosec.
• Digoxin- Its absorption and concentration in the blood are increased when taken along with Prilosec.
• St. John’s wort
• A water pill
• Antibiotics like Rifampin, Amoxicillin, and Clarithromycin.

Prilosec intake is not meant for:

• Patients with known allergy or hypersensitivity to components of Prilosec and medications like Omeprazole.
• Patients who had or are having kidney problems, breathing issues, liver disease, osteoporosis or osteopenia, nausea, vomiting, bloody or black stools, or unexplained weight loss.
• People having pain or difficulty in swallowing.
• People experiencing severe heartburn, lasting for over 3 months.
• People having low magnesium in their blood.
• People taking HIV medication containing Rilpivirine.

Before starting the treatment course with Prilosec take note of the following precautions:

• Avoid drug/disease interactions with Prilosec by sharing information about your current intake of drugs, and illnesses (if any) with your doctor.
• Avoid sudden discontinuation of intake of Prilosec, its overdose, or skipping of the dose.
• Inform the doctor beforehand if pregnant, planning childbearing, or breastfeeding.
• Taking advice from a healthcare provider is important before giving Prilosec OTC to children.
• Take Prilosec as per the doctor’s advice and instructions on the label.
• If experiencing diarrhea on intake of Prilosec or otherwise, talk to a doctor before taking anti-diarrhea medication.

• Store Prilosec capsules/tablets at controlled room temperature, preferably at 20-25℃.
• Keep the supply package tightly closed away from light, heat, and moisture, and out of reach of small children.
• For short periods such as when transporting the medicine, Prilosec can be exposed to temperatures between 15 to 30℃.

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