NAPROSYN (NAPROXEN)

Naprosyn is a brand name for the generic medication Naproxen. In 1994, the FDA-approved the use of naproxen as a non-prescription drug for relieving minor aches and pain caused by different conditions.

Naprosyn contains naproxen sodium as its active ingredient. Naproxen sodium is a white or creamy-colored, odorless, crystalline powder soluble in water and methanol. Its chemical name is 2-naphthaleneacetic acid, 6-methoxy-α-methyl-sodium salt, (S)-. As a nonsteroidal anti-inflammatory drug (NSAID), naproxen sodium works by inhibiting the production of certain chemicals in the body that contribute to pain, inflammation, and fever.  Naprosyn drug formulation does not contain Aspirin, gluten, Ibuprofen, Acetaminophen, and caffeine.

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Naprosyn belongs to a pharmacological class: NSAID (Non-steroidal Anti-Inflammatory Drug). It is a derivative of aryl acetic acid and works by inhibiting prostaglandin production. Prostaglandins contribute to pain, fever, and inflammation in the body. Naprosyn helps alleviate pain, inflammation, and fever by inhibiting the enzymes responsible for prostaglandin synthesis.

Naprosyn comes in the form of oral round tablets, oral caplets, gelcap, or liquid gel of strength 220mg for purchase without a prescription.

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Naprosyn is indicated for temporarily relieving:

Headaches: There are a variety of headaches resulting from irritated nerve endings in different areas of the head and neck. The most common headaches which Naprosyn can relieve include Tension headaches, Cluster Headaches, and migraines.

Back pain and Muscular aches: Acute back and muscle pain are most common among people. Its frequent indicators are dull pain, muscle tightness or stiffness, sharp or stabbing pain, aching muscles, and pain resonating down to the legs. It can be caused by prolonged sitting, poor posture, wearing heavy backpacks, improper lifting of weights, injury/trauma, muscle strain or sprain, and obesity. The most common causes of back pain are strained back muscles or ligaments, severe scoliosis, osteoarthritis, osteoporosis, and ruptured or bulging discs between the spinal bones.

Toothache: It is a sharp, throbbing, or constant pain in or around a tooth that different dental problems can cause. These include an Abscessed tooth, tooth fracture, tooth decay, gum infection or disease, bruxism, and a damaged tooth filling.

Mild arthritis pain: Arthritis is a medical condition characterized by pain, swelling, and stiffness of one or more body joints, thereby causing a reduced range of motion.

Common cold and sinus symptoms:These include nasal congestion, sinus pressure, and headaches.

Menstrual cramps (Dysmenorrhea): These are aches or throbbing pains felt in the lower abdomen just before or/and at the time of menses.

Fever: It is a temporary rising of the internal body temperature because of some underlying illness. Naprosyn can be taken over the counter to get temporary relief from the fever.

• The daily recommended dosage of Naprosyn for Adults is 1 tablet, caplet, liquid gel, or gel cap after every 8-12 hours till the pain, inflammation, or/and fever subsides.
• The adults may take their first dose as 2 tablets for the initial first hour and not exceed that in the first 12-24 hours. They must take the smallest effective dose with a full glass of water.
• If self-medicating, one must not continue taking doses for more than 10 consecutive days in case of pain relief or 3 days for reducing fever.
• One must use Naprosyn as per the description on the product label or as directed by their doctor.
• Children under 12 years may consult their physician before taking Naprosyn.

Naprosyn tablets are meant to be taken orally as a whole with a full glass of water. This indicates that the tablets are intended to be taken orally with a full glass of water.

Crushing or chewing the tablet can alter the drug's intended release and absorption profile, the tablet should be swallowed whole.

Many medications are administered orally because it is convenient and relatively simple for patients to self-administer. By orally ingesting the tablet, it is absorbed into the bloodstream and distributed throughout the body, where it exerts its desired effects.

The use of Naprosyn can cause mild or severe side effects. The most common side effects seen with Naprosyn include:

• Abdominal pain, constipation, diarrhea;
• Headache, LightHeadedness, Dizziness;
• Heartburn, Indigestion, Nausea;
• Tinnitus- ringing in the ears
• Skin rashes, bruising, itching;
• Fluid retention.

Some of the more serious, but rarely reported side effects of Naprosyn, that need prompt medical attention, are:

• Allergic reactions
• Severe stomach bleeding
• Shortness of breath
• Swelling
• Rapid weight gain
• Liver or Kidney problems
• Anemia
• Severe skin reactions
• Hypertension, Heart failure, or attacks
• Blood clots.

Naprosyn may have several possible interactions with other medications. Some of the most common suspected interactions are with:

• Lithium-based medications
• Blood pressure-lowering drugs
• Anticoagulants like Warfarin
• Antimetabolites like Methotrexate or aminoglycosides like gentamicin
• Immuno-suppressive agents like Cyclosporine
• Thiazide diuretics
• Oral diabetes medicine or insulin
• Antidepressants such as escitalopram, citalopram, sertraline (Zoloft), fluoxetine (Prozac), fluvoxamine, trazodone, paroxetine, or vilazodone.

Naprosyn is not safe for use in the following cases:

Absolute contraindications:

• Aspirin allergy
• Before or after cardiac surgery; for relieving perioperative pain in triggering off coronary artery bypass graft (CABG) surgery.

Relative contraindications:

• Bleeding disorders
• Peptic ulcer
• Hepatic disease
• Delayed esophageal transit
• Renal impairment
• Stomatitis
• Late pregnancy.

If taking Naprosyn, people must take the following precautions:

• Avoid intake of alcohol as it may increase the likelihood of stomach bleeding.
• Avoid taking other NSAIDs or any medications/supplements that may interact with Naprosyn.
• Avoid the use of Naprosyn if you have serious illnesses like a history of GI disorders, liver cirrhosis, renal disease, asthma, or increased risk of heart failure or attack and strokes.
• If you have an upset stomach, take Naprosyn with food or milk.
• Do not take Naprosyn right before or after any operation.
• If a pregnant woman or lactating mother, talk to a doctor before using Naprosyn.
• Avoid using expired Naprosyn tablets.
• Avoid intake of Naprosyn tablets, if you have any allergy to any of its ingredients.

• When Naprosyn is not in use, keep the bottle tightly closed at a controlled room temperature (15 to 30℃).
• Store the bottle away from heat, moisture, light, and freezing conditions.
• Keep it out of reach of children.

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