IMITREX NASAL SPRAY (SUMATRIPTAN)

Imitrex is a brand name for a generic medicine for migraine headaches called Sumatriptan, licensed by the GSK group of companies. This prescription drug got FDA approval in 1992 for acute treatment of migraine with or without aura in adults. It is given by a doctor only in cases where migraine headaches have been confirmed diagnosed.

Imitrex nasal spray contains Sumatriptan as its active ingredient in an aqueous buffered solution having the following inactive contents: monobasic potassium phosphate NF, sulfuric acid NF, sodium hydroxide NF, anhydrous dibasic sodium 17 phosphate USP, and purified water USP.

Sumatriptan is a white to off-white powder, a selective 5-hydroxytryptamine1 8 receptor subtype agonist readily soluble in saline and water. Its chemical name is 3-[2-(dimethylamino) ethyl]- 9 N-methyl-1H-indole-5-methanesulfonamide. Want to purchase Imitrex Nasal Spray at a discounted price? Buy Imitrex Online at an affordable price with CanadaPharmacyPro.

Imitrex belongs to the pharmacological class: Serotonin 5-HT1B/1D receptor agonists (Triptans). Imitrex is a serotonin agonist with a high affinity for the 5-HT 1B and 5-HT 1D receptors in the smooth muscle cells of the blood vessels. It goes and binds and stimulates the 5 HT 1B and 5 HT 1D serotonin receptors which mediates the intracranial blood vessel constriction. This action can prevent or abort migraine headaches by shortening the period of the pain in the head and other migraine symptoms.

Imitrex nasal spray comes in two strengths:

• 5 mg: 5mg Imitrex nasal spray has 5 mg of sumatriptan in a 100 microlitre unit dose of aqueous buffered solution having osmolality of 372mOsmol and pH 5.5.
• 20 mg: 20 mg Imitrex nasal spray has 20 mg of sumatriptan in a 100 microlitre unit dose of an aqueous buffered solution having osmolality of 742mOsmol and pH 5.5.

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Imitrex Nasal Spray provides relief from migraine for patients diagnosed with migraine with or without aura.A migraine is a serious headache characterized by intense throbbing pain or a pulsing sensation, usually on one side of the head along with vomiting, nausea, or light sensitivity. Some people experience an aura, before the onset of an actual headache.

• The initial recommended dose is 5mg or 20 mg Imitrex nasal spray as a single spray into one nostril once a day or 10 mg dose as two 5 mg doses in each nostril.
• The doctor prescribes for the second dose only if some response is observed following the first dose. Each dose should be taken in a gap of a minimum of 2 hours.
• The maximum recommended dose in 24 hours is 40 mg.

Imitrex nasal spray is taken through the nose- the nasal opening. This route of administration allows for rapid absorption, making it effective in treating migraine symptoms. Always follow the prescribed dosage and usage instructions provided by your healthcare professional.

Common side effects of using Imitrex nasal spray include:

• Nausea
• Vomiting
• Dizziness, Weakness, or Drowsiness.
• Warm, hot, or burning feeling in the nose and throat.
• Runny or stuffy nose.
• A heavy feeling or pressure in any part of the body.
• Pain or tight feeling in the throat, chest, or jaw.
• Unpleasant or unusual taste in the mouth.

Serious side effects that call for immediate medical attention are:

• Signs of severe allergic reaction.
• Severe chest pain, irregular heartbeat, shortness of breath.
• Symptoms of heart attack.
• Signs of a stroke.
• Raynaud’s syndrome.
• Seizure or Convulsions.
• Blurred vision, severe headache, and pounding in the ears or neck.
• Issues with blood circulation in the legs or feet.
• Severe headaches due to medication overuse.

Imitrex is known to interact with the following:

• Medications for treating serious infections.
• Drugs to treat Parkinson’s disease.
• Medications to treat psychiatric disorders or depression.
• Opioid drugs.
• Medicines to prevent nausea and vomiting.
• MAO inhibitor drugs.
• Stimulant medicine.
• Herbal products.

Imitrex nasal spray is not FDA-cleared or safe for use by:

• Anyone who has known hypersensitivity to the contents of Imitrex nasal spray.
• Patients suffering from heart problems, peripheral vascular disease, uncontrolled hypertension, or a heart disorder called Wolff Parkinson White Syndrome.
• Patients having severe hepatic impairment or ischemic bowel disease.
• Anyone with medical records of coronary artery vasospasm, coronary artery disease, stroke, hemiplegic or basilar migraine, or transient ischemic attack.
• Adults who have used another triptan or an ergotamine-containing medicine within 24 hours.
• Patients who have used monoamine oxidase inhibitors in the past two weeks or are still using them.
• Patients looking for prophylactic therapy for migraine attacks or treatment for cluster headaches.
• Pregnant women.
• Breastfeeding mothers.
• Anyone aged under 18 years.

Before using the Imitrex nasal spray, the doctor recommends the patient follow these precautions:

• Avoid driving or performing any hazardous activity until aware of what effect the Imitrex nasal spray is having on the body. There is a possibility of an impaired reaction.
• Do not use Imitrex nasal spray daily instead use it when having migraine headaches but not within 24 hours before or after using any other antimigraine agent.
• If pregnant or planning to conceive a child or if breastfeeding, inform the doctor beforehand. Do not nurse the child with breast milk within 12 hours of using Imitrex.
• Inform the doctor beforehand about the current intake of medications and supplements and if having any illnesses or allergies.
• Discontinue the use of Imitrex nasal spray if any serious symptoms occur.

• Store Imitrex nasal spray at a controlled temperature between 2°C to 30°C away from intense light, heat, and moisture.
• Do not keep the bottle in a refrigerator and avoid freezing it.

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