FAMVIR

Famvir is a brand name for a generic antiviral medication: Famciclovir. It is a prescription drug that got FDA approval in 1994 for use in the treatment of infections caused by herpes virus, including cold sores, genital herpes, shingles, and chicken pox. The doctors may occasionally prescribe this medication to people developing herpes outbreak around their genitals, mouth, or anus. The drug only helps slow down the growth of the herpes virus and delay its spread so that the body gets enough time to fight off the infection.

Famvir tablets contain famciclovir as its active ingredient along with the following inactive ingredients: polyethylene glycols, hydroxypropyl cellulose, sodium starch glycolate, lactose, magnesium stearate, hydroxypropyl methylcellulose, and titanium dioxide. Famciclovir is a white to pale yellow solid chemically designated as 2-[2-(2-amino-9H-purin-9-yl) ethyl]-1,3-propanediol diacetate. It is an oral prodrug designed for an antiviral agent penciclovir.

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Famvir belongs to the class of drugs known as Purine nucleosides. It is an antiviral drug that aims to reduce the growth and spread of the herpes virus allowing the body to fight off the infection.

Famvir will not cure herpes but it can lessen the symptoms of infections. Famvir is also used in the treatment caused by herpes virus, including cold sores, and shingles.

Famvir is available in the following strengths:

• 125 mg: white, round film-coated, biconvex, beveled edges, imprinted “FAMVIR” on one side and “125” on the other.
• 250 mg: white, round film-coated, biconvex, beveled edges, imprinted “FAMVIR” on one side and “250” on the other.
• 500 mg: white, oval film-coated, biconvex, beveled edges, imprinted “FAMVIR” on one side and “500” on the other.

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Famvir is used in the treatment caused by herpes viruses, including genital herpes, cold sores, and shingles. It also slows down the growth and spread of the herpes virus allowing the body to fight off the infection. It treats shingles caused by herpes zoster. It also helps the sores heal quicker, keeps the new sores from forming, and reduces pain.

Famvir may also be prescribed for long-term use to reduce the frequency and severity of recurrent herpes outbreaks in individuals with frequent recurrences.

The usual adult dose of herpes simplex-Mucocutaneous/immunocompetent host:

Genital herpes:

Initial episode: The initial dose is 250 mg orally taken 3 times a day for 7-10 days. Recurrent episodes: 1000 mg orally twice a day for 1 day; alternatively, 125 mg orally twice a day for 5 days is recommended.

The usual adult dose for Herpes Zoster: is 500 mg orally every 8 hours for 7 days. Famvir is most effective when started within the onset of 48 hours of rash. Its efficacy is not established if started 72 hours after the onset of the rash.

Usual adult dose for herpes simplex suppression:

• Immunocompetent patients: 250 mg orally twice a day.
• HIV-infected patients: 500 mg orally twice a day. 

In the case of Famvir tablets, the route of administration is oral. It is to be taken by mouth. Do not crush, chew, or break a Dulcolax tablet. Swallow the whole tablet with a glass of water. Do not exceed the amount of Famvir than prescribed; it will not make the medicine more effective.

Take Famvir as directed and at the same time every day. It is essential to follow the prescribed dosage and the instructions given by the doctor. It can be taken with or without food.

If you notice the following side effects, it is recommended to consult with your doctor immediately:

• Kidney problems like little or no urination, swelling in feet or ankles, feeling tired or short of breath.
• Headache
• Nausea
• Dizziness
• Yellowing eyes/skin
• Easy bruising/bleeding
• The allergic reaction which includes rash, itching/swelling (especially of the face/throat/tongue).
• Trouble breathing.

Some of the drugs, products, and pills that are known to interact with Famvir include:

• Cladribine
• Digitoxin
• Entecavir
• Pemetrexed
• Probenecid
• Talimogene laherparepvec
• Varicella virus vaccine
• Zoster vaccine live

Before initiating Famvir medication or while on Famvir medication, a few precautions need to be considered which are:

• In the case of renal disease, there are cases of acute renal failure so it is crucial to consult with the doctor.
• In case of pregnancy, it should only be taken after proper consultation with a doctor.
• Famvir is known to interact with liver conditions, so in such cases, it should be avoided or used only under the guidance and approval of a medical professional.
• Avoid sexual intercourse, or use a condom to avoid the spread of the virus to others.

Following are the precautions:

• Avoid taking Famvir in case of liver or kidney conditions.
• In case of allergies or having a hypersensitivity to famvir or any of its components it should be avoided.
• Avoid the consumption of alcohol, it is essential to be cautious. Famvir and alcohol both can affect the liver, so excessive alcohol intake should be avoided.
• Do not take grapefruit while taking this medicine.
• Pregnant and lactating mothers must consult a doctor before taking this medicine.

To ensure proper storage of Famvir tablets, follow these guidelines:

• Keep it at a controlled room temperature between 20-25 degrees Celsius.
• Keep it away from excessive heat, direct sunlight, and moisture.
• Keep it out of reach of children and pets.

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