CALCORT (DEFLAZACORT)

Calcort is a brand name of a generic medication called Deflazacort. It is a prescription medicine manufactured by Neon Healthcare Limited. Its trade name got approval only in the UK and Germany. This steroid medication is given by doctors to treat a wide variety of diseases or medical conditions that require suppression of immune system activity or reduction in inflammation.

Calcort tablets contain Deflazacort as its active ingredient and the following excipients: microcrystalline cellulose, maize starch, lactose monohydrate, and magnesium stearate. If you want to purchase Calcort tablets at a discounted price, buy Calcort online with CanadaPharmacyPro.

Calcort belongs to the pharmacological class of immunosuppressants; Corticosteroids. Corticosteroids are the adrenal gland hormones that have many roles, including control of inflammatory responses. Calcort is a synthetic corticosteroid very effective at reducing inflammation and immune system suppression. It helps avoid tissue damage possible with chronic inflammation.

Calcort works intracellularly to prevent the release of certain chemicals normally involved in producing immune system responses or allergic reactions that result in inflammation. There is a reduction in inflammation because of a decrease in the levels of these chemicals in a particular inflamed site of the body. This helps manage a wide range of conditions associated with inflammation.

Calcort tablets are available in single strength: 6mg. They are white, round, flat, uncoated tablets of 8.5 mm diameter, having a beveled edge, marking of a cross on one side, and “6” embossing on the other side.

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Some of the conditions known to be treatable with Calcort include:

• Asthma, anaphylaxis, or severe hypersensitivity
• Rheumatic carditis.
• Uveitis or optic neuritis.
• Rheumatoid arthritis, Juvenile chronic arthritis, or polymyalgia rheumatica.
• Crohn’s disease or Ulcerative colitis.
• Pemphigus, pyoderma gangrenosum, or bullous pemphigoid.
• Acute interstitial nephritis or nephrotic syndrome.
• Malignant lymphoma, acute and lymphatic leukemia, or multiple myeloma.
• Sarcoidosis, dermatomyositis, mixed connective tissue disease, systemic lupus erythematosus, or polyarteritis nodosa.
• Duchene muscular dystrophy.

• The initial suggested dose for adults having acute disorders is up to 120 mg per day.
• The maintenance prescribed dose for adults having acute disorders is 3 to 18 mg per day.
• The prescribed dose for patients suffering from an acute bronchial asthma attack falls in the range of 48-72 mg per day.

Calcort is available in the form of tablets for oral administration. Take the tablets after having food as per the directions given by the doctor and on the instruction label. This route ensures the medication is absorbed into the bloodstream through the digestive system. It's a common method for many medications because it's generally safe and well-tolerated by most people.

Commonly reported side effects of taking Calcort include:

• Gastrointestinal disturbances.
• Neuropsychiatric problems such as mood.
• Musculoskeletal problems.
• Endocrine conditions.
• Ophthalmic issues.
• Fluid and electrolyte disturbances.
• Impaired healing.
• Skin atrophy.
• Hypersensitivity reactions.
• Acne
• Striae
• Telangiectasia
• Myocardial rupture.
• Menstrual disturbances.
• Glaucoma or Cataracts.
• Increased appetite and weight gain.

• Calcort (Deflazacort) may interact with other drugs, supplements, or substances and have reduced or increased effects on the body.
• Calcort can cause salt and fluid retention and so opposes the effects of other medicines such as anti-hypertensive medications and diuretics (for example, furosemide).
• If Calcort is taken in combination with medications such as amphotericin, acetazolamide, carbenoxolone, beta-agonists such as salmeterol, salbutamol, and terbutaline; theophylline, and potassium-losing diuretics such as Bendroflumethiazide, it can increase risk of hypokalemia- low potassium in the blood.
• Calcort may oppose the effects of antidiabetic medications. It may improve the anti-blood-clotting effect of anticoagulants such as warfarin.

Other drugs that may interact with Calcort and opposite their positive effects include:

• Certain antifungals.
• Certain antibiotics.
• Protease inhibitors.
• Salicylates.
• Non-steroidal anti-inflammatory drugs such as Aspirin.

Intake of Calcort tablets is unsafe for:

• Children and adolescents.
• Old people.
• Individuals who have known hypersensitivity to any of the ingredients of Calcort tablets.
• People who are suffering or have ever had a stroke or blood clot, hypertension, heart disease, kidney disease, liver disease, fluid retention, a stomach or intestinal disorder, microbial infection, or a neuro-muscular disorder such as myasthenia gravis.
• People who have issues with their pituitary gland, thyroid, or adrenal gland.
• People having low mineral density, cataracts, or glaucoma.
• Individuals who ever had an ileostomy or a colostomy.
• Pregnant and breastfeeding women.

Some of the precautions to take while on a treatment course with Calcort include:

• Avoid consumption of grapefruit products and alcohol.
• Do not receive a live-attenuated vaccine for a minimum of 4 to 6 weeks before starting taking the Calcort tablet or while taking it.
• Avoid coming in contact with any sick or infected individual.
• If pregnant, planning to conceive a child, or breastfeeding, inform the doctor beforehand.
• Tell the doctor beforehand about the current intake of medications and supplements and if having any illnesses or allergies.
• Do not change the dosage or stop the intake of Calcort without first consulting the doctor. Avoid overdosing or missing doses.

• Store Calcort tablets in their original packaging at room temperature, preferable at or below 25°C, away from extra heat, moisture, and direct light.
• Do not freeze the tablets.
• Keep it away from the reach of children and pets.

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