BIKTARVY (BICTEGRAVIR/EMTRICITABINE/TENOFOVIR ALAFENAMIDE)

Biktarvy belongs to the class of antiviral combinations. It is used in the treatment of HIV infection. Biktarvy functions by lowering the amount of HIV in the blood helping the immune system to work better. It prevents the replication of HIV in the body helping in decreasing the chances of developing AIDS and HIV-related illnesses like cancer or severe infections.

Biktarvy is the combination of Bictegravir, Emtricitabine, and Tenofovir Alafenamide. It is to be kept in mind that Biktarvy is not a cure for HIV. If you want to buy Biktarvy online at a discounted price, contact the best online pharmacy CanadaPharmacyPro.

Biktarvy belongs to the drug class of Antiviral Combinations that are used for treating viral infections as they use multiple antiviral agents in a single formulation. Combination therapy can be more effective at suppressing viral load and plays a crucial role in managing chronic infections like HIV.

Biktarvy contains three active ingredients:

• Bictegravir: It is an integrase strand inhibitor INSTI.
• Emtricitabine: It is a nucleoside reverse transcriptase inhibitor NRTI.
• Tenofovir Alafenamide: It is a nucleotide reverse transcriptase inhibitor.

Biktarvy is brown, has an oblong shape, and has an imprint of “GSI” and “9883” on the other side.

It is available in the following strengths:

• Bictegravir 50mg
• Tenofovir 25mg
• Emtricitabine 200mg

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Biktarvy is used in treating HIV-1 as it works by preventing the multiplying of HIV in the body and lowers HIV blood levels as well. It reduces the chances of AIDS and HIV- related illness. The medicine is recommended to patients with no history of antiretroviral treatment.

The medicine is also approved for use in pediatric patients and may weight at least 14kg. It has an integrase strand transfer inhibitor that works by blocking the HIV integrase enzyme. This enzyme is used by the virus to integrate its genetic material into the host cell. The medicine also has nucleoside reverse transcriptase inhibitors that affect the virus's ability to replicate as it inhibits the reverse transcriptase enzyme.

• Usual Adult dosage for Adults and pediatric patients (weighing at least 25 kg): Biktarvy (Bictegravir 50mg/ Emtricitabine 200mg/ Tenofovir 25mg) can be taken with or without food 1 tablet once a day
• The usual dosage in pediatric patients weighing at least (14-25) kg: Biktarvy (Bictegravir 30mg/ Emtricitabine 120mg/ Tenofovir 15mg) can be taken with or without food 1 tablet once a day.

Note: Biktarvy is not advised in conditions of severe hepatic impairment.

In the case of Biktarvy tablets, the route of administration is oral. It is to be taken by mouth and is usually administered orally in the form of tablets. It can be taken with or without food, and it should be prohibited with other HIV-1 medicines. The tablets can be swallowed whole or if unable to swallow consult with the doctor they might suggest an alternative way of it.

Do not take Biktarvy in larger or smaller amounts than prescribed by the doctor. In case of taking antacids or supplements containing iron or calcium, Biktarvy should be taken with food simultaneously with these antacids or supplements.

Side effects of Biktarvy:

• Diarrhea
• Nausea
• Headache
• Fatigue
• Insomnia
• Dizziness
• Weight gain
• Depression
• Muscle pain or Weakness
• Increased blood pressure
• Rash
• Abnormal dreams
• Hives
• Difficulty in breathing
• Swelling of face, lips, tongue, or throat.
• Kidney issues like swelling in feet, and no urination.
• Severe liver issues such as dark “tea-colored” urine, stomach- ache, and nausea.

In case of any of these symptoms seek immediate help promptly.

Some of the drugs, products, and pills that are known to interact with Biktarvy include:

• Abametapir Topical
• Acyclovir
• Bacitracin
• Celecoxib
• Diatrizoate
• Enzalutamide
• Fenoprofen
• Ibandronate
• Kanamycin
• Lamivudine
• Magaldrate
• Neomycin
• Olsalazine
• Pamidronate
• Quinine

Before initiating Biktarvy or while on Biktarvy medication, there are a few precautions that need to be considered which include:

• This medicine is not recommended to people with severe hepatic impairment or renal impairment.
• Before taking this medicine one is recommended to go for a hepatitis B infection test or proper renal function monitoring.
• Do not take this medication with drugs like dofetilide or rifampin to prevent the occurrence of severe side effects like dangerous heart rhythms.
• If one is taking aluminum, magnesium, or some antacids or laxatives. They must get them before two hours of taking Biktarvy or six hours after consuming Biktarvy.
• In the case of kidney disease, or hepatitis B virus consult the doctor before initiating Biktarvy medicine.

To ensure the safe and effective use of Biktarvy here are a few precautions which are needed to be considered:

• Avoid taking Biktarvy tablets with antacids containing magnesium as it interferes with the absorption of Biktarvy. Take two hours before or 6 hours before in case of urgency.
• Avoid or limit high-fat meals as they may impact the absorption of drugs.
• Food products containing aluminum, calcium, and iron may reduce the effectiveness of treating HIV infection.
• Do not consume alcohol while taking Biktarvy.
• Avoid taking other medications, including over-the-counter drugs, vitamins, and herbal supplements while taking this medication.
• People with hepatitis B or C must inform their doctor before taking this medication.
• One should not use Biktarvy if allergic to antiviral medicines.

To ensure proper storage of Biktarvy tablets, follow these guidelines:

• Keep it at a controlled room temperature between 20-25 degrees Celsius.
• Keep it away from excessive heat and direct sunlight.
• Keep it out of reach of children or pets.

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