ANTABUSE (DISULFIRAM)

Antabuse is a brand-name medication for a generic drug called Disulfiram. It is a prescription drug that is FDA-approved to overcome drinking problems in alcohol abusers or those with chronic alcoholism. It is given only in adjunct with therapy and counseling support to help people stop drinking alcohol. However, this medicine is not a cure for alcoholism, it can only help prevent unpleasant side effects associated with drinking alcohol.

Antabuse contains Disulfiram as the active ingredient and the following inactive ingredients: sodium bicarbonate, maize starch, magnesium stearate, povidone, colloidal anhydrous silica, tartaric acid, microcrystalline cellulose, purified talc, and polysorbate 20. Disulfiram is an odorless and almost tasteless white to off-white powder with the chemical name bis (diethylthiocarbamoyl) disulfide.

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Antabuse belongs to the pharmacological class: Other Psychiatry agents or Alcohol antagonist drugs. Other psychiatry agents are the class of medications that do not come under any specified class of psychiatric drugs. They are primarily prescribed for the treatment of alcoholism or opioid withdrawal syndrome.

Alcohol antagonists are the drugs that are used in alcohol dependence. They work as a deterrent to alcohol consumption. When one takes alcohol, it gets converted to acetaldehyde and then acetic acid inside the body. Antabuse is an alcohol antagonist that acts to inhibit the activity of enzymes that have a role in the breakdown of alcohol in the body. It works to stop the conversion of acetaldehyde to acetic acid in the body. As a result, there is an upsurge of acetaldehyde in the body which can make one fall sick and reduce one’s desire to consume alcohol.

Antabuse tablets come in two strengths: 250mg and 500mg. They are white, flat, and round tablets scored and marked with CDC. They come in packs of 30 tablets. Contact CanadaPharmacyPro, one of the most reputed and best online pharmacies to get the best Antabuse cost.

Doctors give Antabuse to treat chronic alcoholism or alcohol dependence. Alcohol dependence or Alcoholism is an illness where the intake of excess amounts of alcoholic beverages impacts the mental or physical health of an individual and interferes with the family, social, or occupational responsibilities.

Antabuse helps stop alcohol consumption in people with chronic alcoholism, because alcohol consumption while taking Antabuse can cause very unpleasant side effects, thereby making a person ill. The side effects include nausea, vomiting, fast heartbeat, chest pain, dizziness, thirst, and flushing.

• The initial recommended dosage in the first treatment phase of 1-2 weeks is a maximum of 500 mg daily once a day.
• The average suggested maintenance dosage is 250 mg daily.
• The maximum recommended dosage is 500 mg daily.
• The first dose of Antabuse must be given only when the patient has abstained from alcohol for a minimum of 12 hours.

Antabuse is available in the form of tablets for oral administration. Take the tablet with water either in the morning or before bedtime, daily at the same time. In search of the best and most competitive Antabuse cost? Get in touch with CanadaPharmacyPro, a top online pharmacy. They offer the best pricing. Trust their licensed services for the best Antabuse prices.

The commonly reported side effects of taking Antabuse are:

• Tiredness
• Headache
• Drowsiness
• Skin rash or Acne.
• Metallic or garlic-like taste in the mouth.
• Swollen or sore tongue.
• Impotence or loss of interest in sex.

Some of the unlikely or serious side effects of taking Antabuse include:

• Muscle weakness
• Changes in vision or eye pain/tenderness.
• Numbness, tingling, or weakness of arms and legs.
• Changes in mood or mental health issues.
• Seizures
• Malaise (general feeling of being unwell).
• Loss of appetite
• Nausea
• Vomiting
• Jaundice
• Signs of an allergic reaction.

Inform your doctor, without any delay, if you are feeling unwell or experiencing any other side effects while taking Antabuse.

Some of the drugs known to interact with Antabuse include:

• Phenytoin (seizure medication).
• Isoniazid
• Sleeping tablets like Valium.
• Paraldehyde and Metronidazole.
• Tricyclic antidepressants
• Monoamine oxidase inhibitors.
• Benzodiazepines
• Lithium
• Theophylline
• Blood thinning medications like warfarin, Jantoven, and Coumadin that help stop blood clotting.
• Pain-relieving medications such as Amphetamines, Morphine, Barbiturates, and Pethidine.

This is not an exhaustive list of medications that can interact with Antabuse. Talk to your doctor and pharmacist about your current intake of medications as they have better knowledge on what medications to avoid or take while taking Antabuse.

Antabuse is not safe to be taken by:

• Anyone having an allergy to any of the contents of Antabuse or hypersensitivity to other thiuram derivatives used in rubber vulcanization and pesticides.
• Women who are pregnant or intend to get pregnant.
• People who are taking or have recently received alcohol or alcohol-containing preparations.
• Breastfeeding women.
• Children under the age of 18 years.
• People who have severe myocardial disease, coronary occlusion, or psychoses.
• Patients suffering from heart, kidney, or liver disease; epilepsy, asthma, thyroid problems, diabetes, an allergic skin reaction when coming in contact with skin irritants, organic brain damage, and mental illness with unusual thoughts.
• People having any other complaints other than alcoholism.

When taking Antabuse, it is important to watch for the following:

• Do not take Antabuse in smaller or larger amounts or for a longer duration than recommended.
• Do not make up for missed doses by doubling the dose.
• Do not reduce or stop taking Antabuse, until the doctor advises to do so.
• Do not take Antabuse if it is out of date, the tablets show signs of deterioration, or the package is tampered with.
• Avoid alcohol intake, while on the course of Antabuse as it can cause certain unwanted effects.
• Refrain from the use of consumable products that contain alcohol like stains, paint thinners, sanitizers, solvents, lacquers, and others.
• Keep distance from industries or manufacturing companies that make waxes, dyes, gums, raisins, pesticides, and chemicals to avoid breathing in the toxic fumes.

Store Antabuse tablets in their blistered pack at room temperature, preferably 15-30°C away from light, moisture, heat, and small children.

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