ANDROCUR (CYPROTERONE ACETATE)

Androcur is a brand-name medication for a generic drug called Cyproterone Acetate. It is a prescription drug that got FDA approval for use as an anti-androgen therapy.

Androcur contains Cyproterone Acetate as the active ingredient and the following inactive ingredients: povidone 25000, maize starch, lactose, silicon dioxide (aerosil) (E551), and magnesium stearate (E572). Cyproterone Acetate is chemically designated as 1α,2α-methylene-6-chloro-17α-hydroxypregna-4,6-diene-3,20-dione acetate, and is a synthetic pregnane steroid.

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Androcur belongs to the pharmacological class of Anti-androgen agents.It works to block the activity of androgens and reduce the amount of androgen production in the body of an individual. Androgens are hormones like testosterone- the male sex hormone, which is produced to a greater extent in males than in females. An anti-androgen class of medication is a substance that does not allow the binding of androgens to proteins called androgen receptors, thereby blocking androgen effects on the body.

Androcur tablets come in 50mg and 100mg strengths. Androcur tablets are round and white. They have a scoring of “BV” on one side and a hexagon marking on the other side. Get more information with CanadaPharmacyPro on Androcur cost, one of the best online pharmacies.

Androcur has different uses in men and women:

• In men, doctors prescribe Androcur to slow or stop the growth of cancer and control sexual desire/abnormal sex drive in men who are hypersexual and/or have sexual deviation. In combination with other medications or after testes removal surgery, Androcur may be given to alleviate the side effects such as “night sweats” or “hot flashes” and prevent the worsening of the condition.
• In women, doctors prescribe Androcur to slow or stop the excessive growth of hair, treat scalp hair loss, and reduce the oiliness of the skin to avoid or treat associated skin concerns like acne and dandruff.

• The doctor prescribing Androcur will decide on what dose to take depending on the medical condition being treated.
• The usual suggested dose is one tablet twice daily, preferably after morning and evening meals. Once the tablet provides the desired effect, the dose may be gradually lowered.
• The usual suggested dose for men with prostate cancer is 50-300 mg daily.
• The usual suggested dose for men wanting to reduce their abnormal sex drive is initially 50 mg daily. The maximum dose is 100 mg twice or thrice daily.
• The usual suggested dose for women of childbearing age is 50-100 mg daily starting from 1st day of their cycle to the 10th day of their cycle.
• The usual dose for postmenopausal women or women who have had a hysterectomy is 25-50 mg once a day for 21 days.

Androcur is available in the form of tablets meant for oral administration. These tablets must be swallowed whole with some water after a meal at about the same time daily.

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Commonly reported side effects of taking Androcur include:

• Hot flashes, Sweating.
• Depressed mood.
• Headache
• Shortness of breath.
• A decrease or increase in body weight may be due to fluid retention.
• Restlessness
• Swollen or/ and tender breasts, change in breast size, and breast pain.
• Gastrointestinal complaints including Nausea.
• Irregular menses or Spotting.
• Tiredness
• Liver problems that may be severe or life-threatening.
• Reduced sperm count.
• Reduced ejaculate volume.

The rare or serious side effects of taking Androcur include:

• Skin rashes
• Tender lumps in the breasts and milky fluid oozing out from the nipples.
• Allergic reactions like rash, itch, shortness of breath, and difficulty swallowing or breathing.
• Non-malignant or cancerous liver tumors.
• Osteoporosis

If you experience any of the side mentioned above effects or anything else that worries you, talk to your doctor and get medical treatment.

Some of the drugs known to interact with Androcur include:

• Antifungal medications like Itraconazole, Ketoconazole, and Clotrimazole.
• Ritonavir- a medication to treat HIV.
• Phenytoin- a medication to treat epilepsy.
• St John’s wort- a herbal remedy for mood disorders.
• Antibiotics like Rifampicin.
• HMG-CoA inhibitors (statins)- a class of medications that help lower blood cholesterol levels.
• Medicines like glitazones that treat diabetes.

Talk to your doctor and pharmacist about your current intake of medications as they have better knowledge on what medications to avoid or take while taking Androcur.

Androcur is not safe to be taken by:

• Anyone allergic to any of the contents of Androcur or any other allergies to medicines, food, preservatives, or dyes.
• Patients suffering from diabetes, osteoporosis, blood clots, or sickle cell anemia.
• Patients who have liver disease, any cancer (excluding prostate cancer), wasting diseases (involving unintended weight or muscle loss), Dubin-Johnson or Rotor Syndrome, or severe/ persistent depression.
• People who have ever been diagnosed with a meningioma.
• Women who are pregnant or intend to get pregnant (in the case of male fetus Androcur may lead to feminization).
• Breastfeeding women
• Children under the age of 18 years or those who have underdeveloped testes or bones.

When taking Androcur, it is important to watch for the following:

• Before starting to take Androcur, inform the doctor of any existing allergies or medical conditions, current intake of medications/supplements, whether pregnant or breastfeeding, if want to be fertile after the treatment, and other significant health-related facts.
• Do not make up for missed doses by doubling the dose.
• Do not reduce or stop taking Androcur, until the doctor advises to do so.
• Do not take Androcur if it is out of date, the tablets show signs of deterioration, or the package is torn.
• Avoid alcohol intake, while on the course of Androcur as it can cause certain unwanted effects.
• Do not take Androcur if pregnant or suspected pregnancy as it can affect the developing baby.
• Do not breastfeed while taking Androcur as its active ingredient may pass to the baby through breast milk and may cause harm.
• Be careful while operating machinery or driving until you are aware of how Androcur will affect you.

• Store Androcur tablets in their blistered pack at room temperature, preferably 15-30°C.
• Keep away from light, moisture, heat, and small children.
• It's essential to keep it out of pets.

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